For the vaccination of healthy cattle, 3 months of age or older, as an aid in the prevention of respiratory disease caused by IBR, BVD (Type 2), and BRSV and as an aid in the control of disease caused by BVD (Type 1), PI3, Mannheimia haemolytica and Pasteurella multocida. Duration of immunity (DOI) has been demonstrated to be at least one year for IBR and BVD (Types 1 & 2) and at least 16 weeks for Mannheimia haemolytica and Pasteurella multocida. Additionally, Vista Once SQ is for the vaccination of healthy cows and heifers prior to breeding as an aid in the prevention of fetal infection, including persistently infected calves caused by BVD (Types 1 & 2); and as an aid in the prevention of persistently infected calves caused by BVD (Type 2); and as an aid in the reduction of abortion due to IBR.