For vaccination of healthy cattle using the only avirulent-live culture protection against Pasteurella multocida and Mannheimia haemolytica. Provides modified-live virus vaccine for use against Infectious Bovine Rhinotracheitis (IBR), Bovine Viral Diarrhea (BVD) Type 1 and Type 2, Parainfluenza3 (PI3) and Bovine Respiratory Syncytial Virus (BRSV).